Drugs / SEN0014196
last change Mar 2015 re-read 3 minutes ago

SEN0014196

also known as selisistat
Developed for
Huntington disease
Investigated by
Siena Biotech S.p.A. · European Huntington's Disease Network · Seventh Framework Programme

Trials 4

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT01485965 Nov 2011 → Nov 2012 Huntington disease Siena Biotech S.p.A. Completed No outcome recorded
Phase 1 NCT01485952 Mar → Nov 2011 Huntington disease Siena Biotech S.p.A. Completed No outcome recorded
Phase 1 NCT01521832 Oct 2009 → May 2010 Huntington disease Siena Biotech S.p.A. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01521585 Nov 2011 → Oct 2012 Huntington disease Siena Biotech S.p.A. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as SEN0014196 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01485965 ↗
3

NCT01521585 ↗

NCT01485952 ↗

NCT01521832 ↗

Known as selisistat “Selisistat (SEN0014196), a first-in-class SirT1 inhibitor, is being developed as a disease-modifying therapy for Huntington's disease.” PMID 25223836 ↗ Mar 2015
Action Inhibit “a first-in-class SirT1 inhibitor” PMID 25223836 ↗ Mar 2015
Route Oral “Multiple Oral Doses of SEN0014196” NCT01485952 ↗