Drugs / MACI
MACI
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Withdrawn | EU (EMA) | ChondroCelect | — | 2016-07-29 | europa.eu ↗ |
| Approved | EU (EMA) | ChondroCelect | — | 2009-10-05 | europa.eu ↗ |
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 34 trials · 1 met primary | ||||||
| Phase 3 | NCT06915233 | May 2026 → Jul 2030 expected | chondromalacia | Vericel Corporation | Recruiting | No outcome recorded |
| Phase 3 | NCT03588975 | Oct 2018 → Feb 2030 expected | chondromalacia, osteochondritis dissecans | Vericel Corporation | Recruiting | No outcome recorded |
| Phase 3 | NCT00719576 | Jul 2008 → Mar 2012 | articular cartilage disorder | Vericel Corporation | Completed | Met primary |
| Phase 3 | NCT00414700 | Feb 2002 → Jul 2006 | — | TiGenix n.v. | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT00158613 | Mar 2000 → Nov 2005 | articular cartilage disorder | Vericel Corporation | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | MACI | “Randomized controlled trials studying the efficacy and safety of matrix-applied characterized autologous cultured chondrocytes (MACI) versus microfracture (MFX) for treating...” PMID 24714783 ↗ Apr 20142“MACI (autologous cultured chondrocytes on porcine collagen membrane) versus Bone Marrow Stimulation” NCT06915233 ↗ |
| Known as | Carticel | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00158613 ↗ |
| Known as | ChondroCelect | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00414700 ↗ |
| Modality | Cell therapy | “autologous chondrocyte implantation” PMID 18927254 ↗ Oct 2008 |
| Route | Other | “implanted into the defect” NCT00158613 ↗ |