Drugs / Triazavirin
last change Dec 2021 re-read 9 days ago

Triazavirin

also known as TZV · Riamilovir

Small molecule

Developed for
COVID-19
Investigated by
Perinatal HIV Research Unit of the University of the Witswatersrand · PharmaCentrix (Pty) Ltd · Wits Health Consortium (Pty) Ltd

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2/31 trial
Phase 2/3 NCT04581915 Sep 2020 → Apr 2021 COVID-19 Wits Health Consortium (Pty) Ltd Terminated No outcome recorded
Comparator or background therapy1 trial
Phase 4 NCT04973462 Comparator Aug → Sep 2021 COVID-19 Ain Shams University Unknown No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Triazavirin ClinicalTrials.gov intervention name — accepted as the source's own label NCT04973462 ↗
1

NCT04581915 ↗

Known as Riamilovir “Triazavirin (Riamilovir)” NCT04581915 ↗
Known as TZV “Triazavirin (TZV), a new antiviral drug, has been on the market in Russia since 2015.” NCT04973462 ↗
1

“Triazavirin (TZV)” NCT04581915 ↗

Action Inhibit “The principle mode of action of TZV is inhibiting the synthesis of viral RNA and preventing the replication of genomic fragments.” NCT04973462 ↗
Modality Small molecule “It is a synthetic compound analogue to the purine nucleoside bases.” NCT04973462 ↗
Route Oral “taken orally three times per day” NCT04581915 ↗