Drugs / Abametapir
last change Jul 2020 re-read 2 minutes ago

Abametapir

Small molecule

Developed for
Pediculus humanus capitis infestation
Investigated by
Dr. Reddy's Laboratories Limited

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) XEGLYZE 2020-07-24 fda.gov

Trials 4 · a red edge is where a trial was stopped

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02061813 Jan 2014 Pediculus humanus capitis infestation Dr. Reddy's Laboratories Limited Completed No outcome recorded
Phase 1 NCT01518699 Jan → May 2012 lice infestation Dr. Reddy's Laboratories Limited Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02010333 Apr 2013 → Jul 2014 Pediculus humanus capitis infestation Dr. Reddy's Laboratories Limited Completed No outcome recorded
Phase 2 NCT01336647 Apr → Aug 2011 Pediculus humanus capitis infestation Dr. Reddy's Laboratories Limited Completed No outcome recorded
Also used as a comparator or background therapy in 4 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02062073 Comparator Jan → Mar 2014 Pediculus humanus capitis infestation Dr. Reddy's Laboratories Limited Completed No outcome recorded
Phase 21 trial
Phase 2 NCT02097485 Comparator May → Sep 2014 Pediculus humanus capitis infestation Dr. Reddy's Laboratories Limited Completed No outcome recorded
Phase 32 trials
Phase 3 NCT02060903 Comparator Feb → Jul 2014 Pediculus humanus capitis infestation Dr. Reddy's Laboratories Limited Completed No outcome recorded
Phase 3 NCT02062060 Comparator Feb → Jul 2014 Pediculus humanus capitis infestation Dr. Reddy's Laboratories Limited Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as Abametapir “This study was a randomized, double-blind, placebo- and active-controlled, crossover study that evaluated the potential of Abametapir to prolong cardiac repolarization in...” NCT01518699
6

“HA44 Gel 0.74% comprises of Abametapir as the active pharmaceutical ingredient and Benzyl Alcohol as one of the excipients.” NCT02010333

NCT02061813

NCT02060903

NCT02062060

NCT02097485

NCT02062073

Known as 5,5'-dimethyl-2,2'-dipyridyl ChEMBL registry synonym — accepted as the source's own label CHEMBL2205807
Known as 6,6'-bi-3-picoline ChEMBL registry synonym — accepted as the source's own label CHEMBL2205807
Known as Ha44 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01336647
Known as Xeglyze ChEMBL registry synonym — accepted as the source's own label CHEMBL2205807
Modality Small molecule CHEMBL2205807
Route Topical “Administered topically” NCT01336647