Drugs / PS101
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial · 1 met primary | ||||||
| Phase 1 | NCT04021277 | Sep 2019 → Aug 2024 | colorectal cancer | EXACT Therapeutics AS | Terminated | Met primary Stop: Business |
| Phase 21 trial | ||||||
| Phase 2 | NCT06850623 | Jun 2025 → Dec 2026 expected | pancreatic adenocarcinoma | EXACT Therapeutics AS | Recruiting | No outcome recorded |
News releases announcing trial results or a regulatory action · 6
| Date | Issuer | Release |
|---|---|---|
| 2026-01-27 | EXACT Therapeutics AS | Results Positive initial safety read-out from the Phase 2 ENACT trial in pancreatic cancer, triggering option to exercise warrants exact-tx.com ↗
The TMC concluded that based on the safety cohort data, PS101 was well tolerated and recommends proceeding with the trial as planned. |
| 2025-05-20 | EXACT Therapeutics AS | Results EXACT Therapeutics announces positive final results in Phase 1 ACTIVATE trial in liver metastases from colorectal cancer exact-tx.com ↗
EXACT Therapeutics (Euronext Growth: EXTX), a clinical-stage precision medicine company, is pleased to announce the final and positive data set from its Phase 1 ACTIVATE trial. |
| 2024-04-25 | EXACT Therapeutics AS | Results EXACT Therapeutics presented poster at American Association for Cancer Research exact-tx.com ↗
The results provide proof of concept that treatment with ACT® produces substantial reduction in tumour size in patients treated with standard of care chemotherapeutics. |
| 2023-09-26 | EXACT Therapeutics AS | Results EXACT Therapeutics announces positive clinical results from the ACTIVATE Phase I dose escalation exact-tx.com ↗
EXACT THERAPEUTICS AS (“EXACT-Tx”, Euronext Growth: EXTX), a clinical stage precision health company utilising Acoustic Cluster Therapy (ACT®) across multiple therapeutic areas, today announces positive safety and anticancer activity results from the dose escalation part of the ACTIVATE trial. |
| 2023-05-30 | EXACT Therapeutics AS | Regulatory EXACT Therapeutics Announces Granted Patent in United Kingdom for Acoustic Cluster Therapy (ACT®) exact-tx.com ↗
EXACT THERAPEUTICS AS (“EXACT-Tx”, Euronext Growth: EXTX), a clinical stage precision health company utilising Acoustic Cluster Therapy (ACT®) across multiple therapeutic areas, today announces that Intellectual Property Office in United Kingdom yesterday announced the issuance of UK Patent No. GB2595513 entitled “Treatment of infections”. |
| 2022-03-09 | EXACT Therapeutics AS | Regulatory Exact Therapeutics Announces Clinical Trial Update exact-tx.com ↗
This week the MHRA issued a response to EXACT-Tx requiring an additional submission and approval of documentation regarding the protocol amendment. |
All press releases naming this drug 6 releases
| Date | Issuer | Release |
|---|---|---|
| 2026-01-27 | EXACT Therapeutics AS | Positive initial safety read-out from the Phase 2 ENACT trial in pancreatic cancer, triggering option to exercise warrants exact-tx.com ↗ |
| 2025-05-20 | EXACT Therapeutics AS | EXACT Therapeutics announces positive final results in Phase 1 ACTIVATE trial in liver metastases from colorectal cancer exact-tx.com ↗ |
| 2024-04-25 | EXACT Therapeutics AS | EXACT Therapeutics presented poster at American Association for Cancer Research exact-tx.com ↗ |
| 2023-09-26 | EXACT Therapeutics AS | EXACT Therapeutics announces positive clinical results from the ACTIVATE Phase I dose escalation exact-tx.com ↗ |
| 2023-05-30 | EXACT Therapeutics AS | EXACT Therapeutics Announces Granted Patent in United Kingdom for Acoustic Cluster Therapy (ACT®) exact-tx.com ↗ |
| 2022-03-09 | EXACT Therapeutics AS | Exact Therapeutics Announces Clinical Trial Update exact-tx.com ↗ |
Evidence & citations 2 cited values
Every value below carries the sentence it was read from. 2 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | PS101 | “Drug: PS101; Device: Ultrasound” NCT06850623 ↗ |
| Route | Intravenous | “It is injected into a vein (blood vessel)” NCT04021277 ↗ |