Drugs / MBF-118
last change Sep 2025 re-read 3 minutes ago

MBF-118

Developed for
Crohn disease
Investigated by
Medibiofarma S.L.

Trials 2

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05921916 Jul 2020 → Sep 2022 cancer Medibiofarma S.L. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05940558 Apr 2023 → Sep 2024 Crohn disease Medibiofarma S.L. Completed No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-09-09 Medibiofarma S.L. Results Medibiofarma Successfully Completes Phase 2A Clinical Trial of MBF-118 for Fibrotic Crohn’s Disease medibiofarma.com ↗
The recently completed Phase 2A trial marks a significant milestone, as it is the first trial to demonstrate the excellent safety and tolerability of MBF-118 in patients with Crohn’s Disease.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as MBF-118 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05940558 ↗
1

NCT05921916 ↗

Action Activate “PPAR gamma receptor partial agonist” NCT05921916 ↗
Route Oral “MBF-118 will be administered as single oral ascending dose” NCT05921916 ↗