Drugs / 89Zr-ss-pertuzumab
last change Mar 2024 re-read 3 minutes ago

89Zr-ss-pertuzumab

Diagnostic / imaging agent

Investigated by
Memorial Sloan Kettering Cancer Center · National Institutes of Health (NIH)

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04692831 Nov 2020 → Nov 2027 expected HER2 positive breast carcinoma Memorial Sloan Kettering Cancer Center Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as 89Zr-ss-pertuzumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04692831 ↗
Known as 89Zr-site-specific (ss)-pertuzumab “Here, we describe a first-in-human PET study on patients with HER2-positive breast cancer evaluating the safety, biodistribution, and dosimetry of 89Zr-site-specific...” PMID 38272704 ↗ Mar 2024
Modality Diagnostic / imaging agent “89Zr-ss-pertuzumab PET/CT was used to assess HER2 status and heterogeneity to guide biopsy and decide the next line of treatment at progression.” PMID 38272704 ↗ Mar 2024
Route Intravenous “Patients were administered 74 MBq of 89Zr-ss-pertuzumab in 20 mg of total antibody intravenously and underwent PET/CT at 1 d, 3-4 d, and 5-8 d after injection.” PMID 38272704 ↗ Mar 2024