Drugs / CD19CAR-CD3Zeta-4-1BB-Expressing Autologous T-Lymphocyte Cells
last change Jul 2026 re-read 3 minutes ago

CD19CAR-CD3Zeta-4-1BB-Expressing Autologous T-Lymphocyte Cells

also known as UCD19 CAR-T

Cell therapy targets CD19

Developed for
B-cell acute lymphoblastic leukemia
Investigated by
Children's Hospital Colorado · University of Colorado, Denver

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04544592 Mar 2021 → Jun 2026 overdue B-cell acute lymphoblastic leukemia University of Colorado, Denver Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as CD19CAR-CD3Zeta-4-1BB-Expressing Autologous T-Lymphocyte Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT04544592 ↗
Known as UCD19 CAR-T “We hypothesize that CD19-directed CAR-T cells manufactured using the Miltenyi CliniMACs Prodigy System (UCD19 CAR-T) will be safe, well-tolerated, and show preliminary efficacy...” NCT04544592 ↗
Modality Cell therapy “This phase I/II trial will investigate a new CD19 directed CAR-T therapy manufactured locally” NCT04544592 ↗
Target CD19 “The CD19 CAR used in this study consists of three main components” NCT04544592 ↗