Drugs / LNS8801
last change Aug 2026 re-read 9 days ago

LNS8801

also known as CHEMBL569766 · ML051

Small molecule targets GPER1 via activation

Developed for
cancer · cutaneous melanoma
Investigated by
Linnaeus Therapeutics, Inc. · Merck Sharp & Dohme LLC

Trials 2

2020202120222023202420252026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT04130516 Oct 2019 → Jun 2026 overdue cancer Linnaeus Therapeutics, Inc. Active not recruiting No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT06624644 Aug 2025 → Feb 2029 expected cutaneous melanoma Linnaeus Therapeutics, Inc. Recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as LNS8801 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06624644 ↗
1

NCT04130516 ↗

Known as CHEMBL569766 ChEMBL registry synonym — accepted as the source's own label CHEMBL569766 ↗
Known as ML051 ChEMBL registry synonym — accepted as the source's own label CHEMBL569766 ↗
Action Activate “selective agonist of GPER” NCT04130516 ↗
Modality Small molecule — CHEMBL569766 ↗
Route Oral “LNS8801 will be administered orally” NCT04130516 ↗
Target GPER “selective agonist of GPER” NCT04130516 ↗