Drugs / COR-101
last change Feb 2026 re-read 3 minutes ago

COR-101

Monoclonal antibody

Developed for
COVID-19
Investigated by
Corat Therapeutics Gmbh

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04674566 Apr 2021 → Oct 2022 COVID-19 Corat Therapeutics Gmbh Unknown No outcome recorded

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2021-06-22 Corat Therapeutics Gmbh Results CORAT antibody COR-101 binds and inhibits all B.1.617 SARS-CoV-2 variants, including the fast proliferating “delta” variant corat-therapeutics.com ↗
Our laboratory tests indicate that COR-101 recognizes the particularly aggressive new „delta” variant B.1.617.2, which is rapidly replacing the “alpha” variant B.1.1.7
2020-12-18 Corat Therapeutics Gmbh Results Human SARS-CoV-2 neutralizing antibody COR-101 demonstrates high efficacy in a COVID-19 animal model and is ready to be used in clinical studies to treat COVID-19 patients corat-therapeutics.com ↗
It induced recovery of SARS-CoV-2 infected hamsters within two days.
2020-12-04 Corat Therapeutics Gmbh Results How human antibody COR-101 neutralizes the coronavirus SARS-CoV-2 corat-therapeutics.com ↗

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as COR-101 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04674566 ↗
Modality Monoclonal antibody “COR-101, a novel mAb with a silenced Fc region designed to minimize antibody-dependent enhancement” PMID 41654452 ↗ Feb 2026
Route Intravenous “Administered intravenously (IV) single dose” NCT04674566 ↗