Drugs / UZATRESGENE AUTOLEUCEL
last change Dec 2023 re-read 3 minutes ago

UZATRESGENE AUTOLEUCEL

Cell therapy

Developed for
esophageal cancer · gastroesophageal cancer · endometrial cancer · gastric cancer · head and neck cancer · melanoma · non-small cell lung carcinoma · ovarian cancer
+1 more · urothelial carcinoma
Investigated by
Adaptimmune · ICON plc · USWM CT, LLC

Trials 2

20202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04044859 Aug 2019 → Dec 2026 expected endometrial cancer, esophageal cancer, gastric cancer, gastroesophageal cancer +5 USWM CT, LLC Active not recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT04752358 Sep 2021 → Jun 2023 esophageal cancer, gastroesophageal cancer Adaptimmune Terminated No outcome recorded Stop: Enrollment

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as UZATRESGENE AUTOLEUCEL ChEMBL registry synonym — accepted as the source's own label CHEMBL6068465 ↗
Known as ADP-A2M4CD8 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04752358 ↗
1

NCT04044859 ↗

Known as Uzatresgen autoleucel ChEMBL registry synonym — accepted as the source's own label CHEMBL6068465 ↗
Modality Cell therapy “ADP-A2M4CD8 T-cell therapy” NCT04044859 ↗
Route Other “Infusion of autologous genetically modified ADP-A2M4CD8 on Day 1” NCT04044859 ↗