Drugs / recombinant hepatitis B vaccine
recombinant hepatitis B vaccine
Trials 9 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2/32 trials | ||||||
| Phase 2/3 | NCT03919578 | Sep 2019 → Jan 2020 | — | PT Bio Farma | Completed | No outcome recorded |
| Phase 2/3 | NCT01203319 | Nov 2006 → Dec 2010 | hepatitis B virus infection | Jiangsu Province Centers for Disease Control and Prevention | Completed | No outcome recorded |
| Phase 47 trials | ||||||
| Phase 4 | NCT03962803 | Jun 2019 → Feb 2020 | hepatitis B virus infection | Shanxi Medical University | Unknown | No outcome recorded |
| Phase 4 | NCT03962816 | May 2019 → Feb 2020 | hepatitis B virus infection | Shanxi Medical University | Unknown | No outcome recorded |
| Phase 4 | NCT03962881 | May 2019 → Feb 2020 | hepatitis B virus infection | Shanxi Medical University | Unknown | No outcome recorded |
| Phase 4 | NCT06209398 | May 2018 → Dec 2024 | hand, foot and mouth disease | Jiangsu Province Centers for Disease Control and Prevention | Unknown | No outcome recorded |
| Phase 4 | NCT03274102 | Apr → Nov 2017 | hand, foot and mouth disease | Sinovac Biotech Co., Ltd | Completed | No outcome recorded |
| Phase 4 | NCT02764671 | May 2015 → Sep 2020 | hepatitis B virus infection | Shenzhen Kangtai Biological Products Co., LTD | Unknown | No outcome recorded |
| Phase 4 | NCT02732054 | Mar 2015 → Feb 2016 | hepatitis B virus infection | Chiang Mai University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 4 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT04075201 Comparator | Jul 2019 → May 2021 | hepatitis B virus infection | Sinovac Biotech Co., Ltd | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT01453348 Comparator | Oct 2011 → Jan 2012 | hepatitis A virus infection, hepatitis B virus infection, meningococcal meningitis | Novartis Vaccines | Completed | No outcome recorded |
| Phase 3 | NCT01183611 Comparator | Apr 2007 → Jun 2010 | Hepadnaviridae infectious disease | Jiangsu Province Centers for Disease Control and Prevention | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT01412567 Comparator | Oct 2005 → Jun 2010 | chronic hepatitis B virus infection | Govind Ballabh Pant Hospital | Completed | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 15 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | recombinant hepatitis B vaccine | “This study tested the hypothesis that the immunogenicity and safety of the simultaneous administration of enterovirus 71 (EV71) vaccine (dose 1) with recombinant hepatitis B...” PMID 30891604 ↗ Jul 201912“Recombinant hepatitis B vaccine at birth, 6 weeks, 10 weeks, and 14 weeks in the dose of 10 mcg (0.5 mL), by intramuscular injection in the anterolateral thigh” NCT01412567 ↗ “This is a phase Ⅰ clinical trial of recombinant hepatitis B vaccine (Hansenula polymorpha,10μg)” NCT04075201 ↗ |
| Known as | HB vaccine | “Alternative schedules are needed to provide greater immunogenicity in adults who fail to respond to the standard hepatitis B (HB) vaccine regimen.” PMID 24681228 ↗ Mar 2014 |
| Known as | HepB | “This study tested the hypothesis that the immunogenicity and safety of the simultaneous administration of enterovirus 71 (EV71) vaccine (dose 1) with recombinant hepatitis B...” PMID 30891604 ↗ Jul 2019 |
| Known as | recombinant HBV vaccine | “Immediately after delivery, babies were randomized to receive either HBIG or placebo in addition to recombinant HBV vaccine (at 0, 6, 10 and 14 weeks).” PMID 24168259 ↗ Apr 2013 |
| Modality | Vaccine | “This study is designed to investigate the safety, reactogenicity, and immunogenicity of 10ug recombinant hepatitis B vaccine (yeast).” NCT01183611 ↗ |
| Route | Intramuscular | “by intramuscular injection in the anterolateral thigh” NCT01412567 ↗ |