Drugs / antithymocyte globulins
last change Feb 2017 re-read 9 days ago

antithymocyte globulins

also known as ATG
Developed for
eosinophilic granulomatosis with polyangiitis
Investigated by
Mounzer Agha · Nantes University Hospital · University Hospital, Toulouse

Trials 3

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT02728271 Apr → Jul 2016 eosinophilic granulomatosis with polyangiitis Mounzer Agha Terminated No outcome recorded
Phase 42 trials
Phase 4 NCT02056938 Jun 2014 → Feb 2017 — Nantes University Hospital Terminated No outcome recorded Stop: Enrollment
Phase 4 NCT00538265 May 2005 → Jan 2010 — University Hospital, Toulouse Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as antithymocyte globulins “Administration of total lymphatic irradiation, antithymocyte globulins, and high dose cyclophosphamide, followed by the infusion of autologous stem cells.” NCT02728271 ↗
2

“combining induction therapy with 3 injections of antithymocyte globulins (ATG) (1.5 mg/kg/d at D0, D2 and D4)” NCT00538265 ↗

NCT02056938 ↗

Known as ATG “Anti-Thymocyte Globulins (ATG) as induction therapy has been described as a possible treatment for reducing the prevalence of Delayed Graft Function (DGF).” PMID 26099226 ↗ Jun 2015
1

“combining induction therapy with 3 injections of antithymocyte globulins (ATG) (1.5 mg/kg/d at D0, D2 and D4)” NCT00538265 ↗

Route Intravenous “will be infused over a period of at least 6 hours” NCT00538265 ↗