Drugs / Tefinostat
last change Dec 2018 re-read 3 minutes ago

Tefinostat

also known as CHR-2845

Small molecule

Developed for
hepatocellular carcinoma · lymphoma
Investigated by
Chroma Therapeutics · Queen Mary University of London

Trials 2

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00820508 Dec 2008 → Jul 2011 lymphoma Chroma Therapeutics Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02759601 Jan 2013 → Dec 2018 hepatocellular carcinoma Queen Mary University of London Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as tefinostat “Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase inhibitor (HDACi).” PMID 23647373 ↗ May 2013
1

NCT02759601 ↗

Known as CHR-2845 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00820508 ↗
Action Inhibit “Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase inhibitor (HDACi).” PMID 23647373 ↗ May 2013
Modality Small molecule — CHEMBL4297582 ↗
Route Oral “oral, once daily tefinostat” PMID 23647373 ↗ May 2013