Drugs / TNG348
last change May 2024 re-read 2 minutes ago

TNG348

targets USP1 via inhibition

Developed for
BRCA1-related cancer predisposition · hereditary breast carcinoma · malignant pancreatic neoplasm · ovarian carcinoma · prostate cancer
Investigated by
Tango Therapeutics, Inc.

Trials 1 · a red edge is where a trial was stopped

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT06065059 Dec 2023 → May 2024 BRCA1-related cancer predisposition, hereditary breast carcinoma, malignant pancreatic neoplasm, ovarian carcinoma +1 Tango Therapeutics, Inc. Terminated No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as TNG348 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06065059
Action Inhibit “Ubiquitin Specific Peptidase 1 (USP1) inhibitor” NCT06065059
Target USP1 “Ubiquitin Specific Peptidase 1 (USP1) inhibitor” NCT06065059