Drugs / RO6839921
last change Feb 2020 re-read 3 minutes ago

RO6839921

targets MDM2 via inhibition

Developed for
acute myeloid leukemia
Investigated by
Hoffmann-La Roche

Trials 1

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02098967 Apr 2014 → May 2018 acute myeloid leukemia Hoffmann-La Roche Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as RO6839921 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02098967 ↗
Action Inhibit “RO6839921 is an inactive pegylated prodrug of the oral MDM2 antagonist idasanutlin” PMID 32020437 ↗ Feb 2020
Route Intravenous “In both arms, RO6839921 will be administered by IV infusion on Days 1-5 of 28-day cycles.” NCT02098967 ↗
Target MDM2 “RO6839921 is an inactive pegylated prodrug of the oral MDM2 antagonist idasanutlin” PMID 32020437 ↗ Feb 2020