Drugs / IDE574
last change Apr 2026 re-read 9 days ago

IDE574

Small molecule targets KAT7 via inhibition

Developed for
castration-resistant prostate carcinoma · colorectal carcinoma · estrogen-receptor positive breast cancer · non-small cell lung carcinoma
Investigated by
IDEAYA Biosciences

Trials 1

2027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07540572 Mar 2026 → Mar 2030 expected castration-resistant prostate carcinoma, colorectal carcinoma, estrogen-receptor positive breast cancer, non-small cell lung carcinoma IDEAYA Biosciences Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2026-03-18 IDEAYA Biosciences Results IDEAYA Biosciences Announces Upcoming Presentations at AACR 2026 Highlighting Multiple Clinical Stage Pipeline Programs ideayabio.com ↗
The KAT6/7 inhibitor IDE574 disrupts tumor lineage identity and drug tolerance to deliver robust antitumor activity in biomarker selected indications
2025-12-10 IDEAYA Biosciences Regulatory IDEAYA Biosciences Announces IND Submission for IDE574, a Potential First-In-Class KAT6/7 Dual Inhibitor for Breast and Lung Cancers ideayabio.com ↗

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as IDE574 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07540572 ↗
Action Inhibit “small molecule inhibitor that co-targets” NCT07540572 ↗
Modality Small molecule “IDE574 is a synthetically manufactured small molecule inhibitor” NCT07540572 ↗
Target KAT7 “IDE574 is a synthetically manufactured small molecule inhibitor that co-targets the lysine acetyltransferase enzymes KAT6 and KAT7.” NCT07540572 ↗