Drugs / PROPANTHELINE
PROPANTHELINE
also known as
Propantheline Bromide · Bromure de propantheline · Bromuro de propantelina · NSC-757294 · Pro-banthine · Propantheline cation · Propantheline ion
Small molecule targets CHRM1, CHRM2, CHRM3 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | PRO-BANTHINE | — | 1953-04-02 | fda.gov ↗ |
Trials 1
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 41 trial | ||||||
| Phase 4 | NCT01010048 | Oct 2009 | urolithiasis | Chongqing Medical University | Unknown | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 1 | NCT01640002 Comparator | May → Oct 2012 | human T-lymphotropic virus 1 infectious disease | Hospital Universitário Professor Edgard Santos | Unknown | No outcome recorded |
Evidence & citations 13 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | PROPANTHELINE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1180725 ↗ |
| Known as | Bromure de propantheline | ChEMBL registry synonym — accepted as the source's own label CHEMBL1180725 ↗ |
| Known as | Bromuro de propantelina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1180725 ↗ |
| Known as | NSC-757294 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1180725 ↗ |
| Known as | Pro-banthine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1180725 ↗ |
| Known as | Propantheline Bromide | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01640002 ↗ |
| Known as | Propantheline cation | ChEMBL registry synonym — accepted as the source's own label CHEMBL1180725 ↗ |
| Known as | Propantheline ion | ChEMBL registry synonym — accepted as the source's own label CHEMBL1180725 ↗ |
| Action | Inhibit | “Muscarinic acetylcholine receptor M2 antagonist” CHEMBL1180725 ↗2“Muscarinic acetylcholine receptor M1 antagonist” CHEMBL1180725 ↗ “Muscarinic acetylcholine receptor M3 antagonist” CHEMBL1180725 ↗ |
| Modality | Small molecule | — CHEMBL1180725 ↗ |
| Target | CHRM1 | “Muscarinic acetylcholine receptor M1 antagonist” CHEMBL1180725 ↗ |
| Target | CHRM2 | “Muscarinic acetylcholine receptor M2 antagonist” CHEMBL1180725 ↗ |
| Target | CHRM3 | “Muscarinic acetylcholine receptor M3 antagonist” CHEMBL1180725 ↗ |