Drugs / HL 10
last change Jul 2010 re-read 3 minutes ago

HL 10

Protein / enzyme biologic

Developed for
acute lung injury · acute respiratory distress syndrome
Investigated by
LEO Pharma

Trials 1

2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT00742482 Jan 2003 → Jan 2005 acute lung injury, acute respiratory distress syndrome LEO Pharma Terminated Missed primary

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as HL 10 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00742482 ↗
Modality Protein / enzyme biologic “We randomly assigned 418 patients to receive usual care either with or without instillation of exogenous natural porcine surfactant HL 10 as large boluses.” PMID 19713451 ↗ Aug 2009
Route Other “Intratracheal surfactant replacement induces a significant and prolonged lung reaeration.” PMID 20633284 ↗ Jul 2010