Drugs / 3,4-methylenedioxymethamphetamine
last change Oct 2012 re-read 3 minutes ago

3,4-methylenedioxymethamphetamine

also known as MDMA

targets CYP2D6 via inhibition

Investigated by
National Institute on Drug Abuse (NIDA) · Parc de Salut Mar

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01447472 May 2003 → May 2009 — Parc de Salut Mar Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as 3,4-methylenedioxymethamphetamine “The synthetic psychostimulant MDMA (± 3,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based...” PMID 23112822 ↗ Oct 2012
Known as MDMA ClinicalTrials.gov intervention name — accepted as the source's own label NCT01447472 ↗
Action Inhibit “mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6)” PMID 23112822 ↗ Oct 2012
Route Oral “A single oral weight-adjusted dose of MDMA was administered” PMID 23112822 ↗ Oct 2012
Target CYP2D6 “mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6)” PMID 23112822 ↗ Oct 2012