Drugs / Elinogrel
last change May 2012 re-read 2 minutes ago

Elinogrel

Small molecule targets P2RY12 via inhibition

Developed for
myocardial infarction
Investigated by
Portola Pharmaceuticals · Alexion Pharmaceuticals, Inc. · Novartis

Trials 3 · a red edge is where a trial was stopped

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00984113 Sep → Dec 2009 impaired renal function disease Portola Pharmaceuticals Terminated No outcome recorded
Phase 22 trials
Phase 2 NCT00751231 Dec 2008 → Apr 2010 Portola Pharmaceuticals Completed No outcome recorded
Phase 2 NCT00546260 Nov 2007 → Jul 2008 myocardial infarction Alexion Pharmaceuticals, Inc. Terminated No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as elinogrel “Safety and feasibility of adjunctive antiplatelet therapy with intravenous elinogrel, a direct-acting and reversible P2Y12 ADP-receptor antagonist, before primary percutaneous...” PMID 19958867 Dec 2009
1

NCT00984113

Known as ELINOGREL POTASSIUM ChEMBL registry synonym — accepted as the source's own label CHEMBL2103828
Known as Elinogrel potassium salt ChEMBL registry synonym — accepted as the source's own label CHEMBL2103828
Known as PRT-060128 POTASSIUM ChEMBL registry synonym — accepted as the source's own label CHEMBL2103828
Known as PRT060128 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00751231
Action Inhibit “a competitive, reversible intravenous and oral P2Y(12) inhibitor” PMID 22647518 May 2012
1

“Purinergic receptor P2Y12 antagonist” CHEMBL2103828

Modality Small molecule CHEMBL2103828
Route Intravenous “elinogrel administered as a single intravenous bolus” PMID 19958867 Dec 2009
Target P2RY12 “Purinergic receptor P2Y12 antagonist” CHEMBL2103828