Drugs / GGTI-2418
last change Aug 2025 re-read 3 minutes ago

GGTI-2418

also known as PTX-100

Small molecule

Developed for
cancer of unknown primary site · primary cutaneous T-cell lymphoma
Investigated by
Prescient Therapeutics, Ltd.

Trials 2

202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03900442 Sep 2019 → Jul 2025 cancer of unknown primary site Prescient Therapeutics, Ltd. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06854653 Mar 2025 → Jan 2028 expected primary cutaneous T-cell lymphoma Prescient Therapeutics, Ltd. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as GGTI-2418 “Phase 1 Pharmacodynamic and Pharmacokinetic Study of the Geranylgeranyltransferase I Inhibitor PTX-100 (GGTI-2418) in Patients With Advanced Malignancies” NCT03900442 ↗
Known as PTX-100 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06854653 ↗
1

NCT03900442 ↗

Action Inhibit “Geranylgeranyltransferase I Inhibitor PTX-100” NCT03900442 ↗
Modality Small molecule — CHEMBL3218390 ↗
Route Intravenous “PTX-100 will be administered by IV infusion over 60 minutes” NCT03900442 ↗