Drugs / Teprotumumab N01
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Teprotumumab N01

Monoclonal antibody targets IGF1R via inhibition

Developed for
disease of orbital part of eye adnexa · endocrine exophthalmos · optic nerve disorder
Investigated by
Innovent Biologics (Suzhou) Co. Ltd. · Sun Yat-sen University

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT07594912 Aug 2026 → Dec 2027 expected disease of orbital part of eye adnexa, optic nerve disorder Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 41 trial
Phase 4 NCT07265258 Dec 2025 → Sep 2026 overdue endocrine exophthalmos Innovent Biologics (Suzhou) Co. Ltd. Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Teprotumumab N01 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07594912 ↗
1

NCT07265258 ↗

Action Inhibit “IGF-1R inhibitor” NCT07594912 ↗
Modality Monoclonal antibody “Insulin-like growth factor-1 receptor monoclonal antibody” NCT07594912 ↗
Route Intravenous “Participants will be randomized 1:1 to receive either intravenous teprotumumab N01” PMID 42448986 ↗ Jul 2026
Target IGF1R “IGF-1R inhibitor” NCT07594912 ↗