Drugs / AERAS-402

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT01683773 Sep 2012 → Aug 2014 tuberculosis University of Oxford Completed No outcome recorded
Phase 1 NCT02375256 Oct 2009 → Dec 2010 tuberculosis Aeras Completed No outcome recorded
Phase 1 NCT02430506 Sep 2008 → Jun 2009 tuberculosis Aeras Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01198366 Sep 2010 → Jan 2014 tuberculosis Aeras Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01017536 Dec 2009 → Mar 2012 HIV infectious disease, tuberculosis Aeras Completed No outcome recorded
Phase 2 NCT02414828 Oct 2008 → Jul 2010 tuberculosis Aeras Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01378312 Comparator Feb → Oct 2011 tuberculosis Aeras Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as AERAS 402 AERAS 402 is a live recombinant serotype 35 replication deficient adenovirus vector expressing a fusion protein of three Mycobacterium tuberculosis (Mtb) antigens (Ag85A, Ag85B...” NCT01198366
7

“AERAS-402, a recombinant, replication-deficient adenovirus type 35 expressing the protective M. tuberculosis antigens Ag85A, Ag85B, and TB10.4” PMID 22296955 Jan 2012

NCT01017536

NCT02430506

NCT01198366

NCT01683773

NCT02375256

NCT02414828

Modality Vaccine “adenovirus vaccineNCT01198366
Route Intramuscular “0.5 mL IM injection of 3 x 1010vp AERAS-402 on Study Days 0 and 28” NCT01378312