Drugs / BMS-387032
last change Mar 2009 re-read 3 minutes ago

BMS-387032

also known as SNS-032

Small molecule targets CDK2, CDK7, CDK9 via inhibition

Developed for
B-cell chronic lymphocytic leukemia · mantle cell lymphoma · neoplasm · plasma cell myeloma
Investigated by
Sunesis Pharmaceuticals

Trials 2

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00446342 Feb 2007 → Dec 2008 B-cell chronic lymphocytic leukemia, mantle cell lymphoma, plasma cell myeloma Sunesis Pharmaceuticals Completed No outcome recorded
Phase 1 NCT00292864 Jan 2006 → Dec 2007 neoplasm Sunesis Pharmaceuticals Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as BMS-387032 ChEMBL registry synonym — accepted as the source's own label CHEMBL296468 ↗
Known as SNS-032 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00292864 ↗
1

NCT00446342 ↗

Action Inhibit “SNS-032, a Novel Cyclin-Dependent Kinase Inhibitor” NCT00292864 ↗
3

“Cyclin-dependent kinase 9 inhibitor” CHEMBL296468 ↗

“Cyclin-dependent kinase 2 inhibitor” CHEMBL296468 ↗

“Cyclin-dependent kinase 7 inhibitor” CHEMBL296468 ↗

Modality Small molecule — CHEMBL296468 ↗
Route Intravenous “one-hour infusions given once daily for 5 consecutive days” NCT00292864 ↗
Target CDK2 “Cyclin-dependent kinase 2 inhibitor” CHEMBL296468 ↗
Target CDK7 “Cyclin-dependent kinase 7 inhibitor” CHEMBL296468 ↗
Target CDK9 “Cyclin-dependent kinase 9 inhibitor” CHEMBL296468 ↗