Drugs / JKB-122
last change Feb 2024 re-read 3 minutes ago

JKB-122

targets TLR4 via inhibition

Developed for
autoimmune hepatitis · chronic hepatitis C virus infection · metabolic dysfunction-associated steatohepatitis
Investigated by
TaiwanJ Pharmaceuticals Co., Ltd

Trials 4

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 24 trials
Phase 2 NCT04371718 Nov 2020 → Nov 2023 autoimmune hepatitis TaiwanJ Pharmaceuticals Co., Ltd Unknown No outcome recorded
Phase 2 NCT04255069 Jun 2020 → Jun 2023 metabolic dysfunction-associated steatohepatitis TaiwanJ Pharmaceuticals Co., Ltd Unknown No outcome recorded
Phase 2 NCT02556372 Apr 2016 → Jan 2019 autoimmune hepatitis TaiwanJ Pharmaceuticals Co., Ltd Completed No outcome recorded
Phase 2 NCT02293941 May 2014 → Aug 2017 chronic hepatitis C virus infection TaiwanJ Pharmaceuticals Co., Ltd Terminated No outcome recorded
Comparator or background therapy1 trial
Phase 1 NCT04313205 Comparator Aug → Dec 2020 autoimmune hepatitis TaiwanJ Pharmaceuticals Co., Ltd Unknown No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as JKB-122 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02293941 ↗
4

NCT04371718 ↗

NCT02556372 ↗

NCT04313205 ↗

NCT04255069 ↗

Action Inhibit “JKB-122 is a TLR4 antagonist and will be administrated in capsule or tablet form” NCT04313205 ↗
Route Oral “5mg, oral, once daily” NCT02293941 ↗
Target TLR4 “JKB-122 is a TLR4 antagonist and will be administrated in capsule or tablet form” NCT04313205 ↗