Drugs / NC525
last change Jan 2025 re-read 3 minutes ago

NC525

Monoclonal antibody targets LAIR1

Developed for
acute myeloid leukemia · chronic myelomonocytic leukemia · myelodysplastic syndrome
Investigated by
NextCure, Inc.

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05787496 Feb 2023 → Jan 2025 acute myeloid leukemia, chronic myelomonocytic leukemia, myelodysplastic syndrome NextCure, Inc. Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as NC525 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05787496 ↗
Modality Monoclonal antibody “Monoclonal antibody specific for LAIR-1” NCT05787496 ↗
Route Intravenous “Subjects received NC525 IV at 2mg/kg bi-weekly (Q2W) for Cycles 1-6, followed by every 4 weeks (Q4W) thereafter.” NCT05787496 ↗
Target LAIR1 “Monoclonal antibody specific for LAIR-1” NCT05787496 ↗