Drugs / seletalisib
last change Mar 2021 re-read 3 minutes ago

seletalisib

also known as UCB5857

Small molecule targets PIK3CD via inhibition

Developed for
psoriasis · Sjogren syndrome
Investigated by
Parexel · UCB Celltech · PRA Health Sciences · UCB Pharma

Trials 3

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02207595 Aug 2014 → Feb 2015 — UCB Celltech Completed No outcome recorded
Phase 1 NCT02303509 Aug 2013 → Feb 2014 psoriasis UCB Pharma Completed No outcome recorded
Phase 21 trial
Phase 2 NCT02610543 Oct 2015 → Sep 2017 Sjogren syndrome UCB Celltech Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as seletalisib “A phase 2 randomized, double-blind, placebo-controlled, proof-of-concept study of oral seletalisib in primary Sjögren's syndrome.” PMID 32949140 ↗ Mar 2021
Known as UCB5857 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02207595 ↗
1

NCT02303509 ↗

Action Inhibit “seletalisib, a potent and selective PI3Kδ inhibitor” PMID 32949140 ↗ Mar 2021
1

“PI3-kinase p110-delta subunit inhibitor” CHEMBL4297648 ↗

Modality Small molecule — CHEMBL4297648 ↗
Route Oral “Route of Administration: Oral Use” NCT02207595 ↗
Target PIK3CD “PI3-kinase p110-delta subunit inhibitor” CHEMBL4297648 ↗