Drugs / TZP-102
last change Jul 2013 re-read 3 minutes ago

TZP-102

Protein / enzyme biologic targets GHSR via activation

Developed for
gastroparesis
Investigated by
Tranzyme, Inc.

Trials 3

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01664637 Aug 2012 → Jan 2013 gastroparesis Tranzyme, Inc. Terminated Missed primary
Phase 2 NCT01452815 Sep 2011 → Nov 2012 gastroparesis, type 1 diabetes mellitus, type 2 diabetes mellitus Tranzyme, Inc. Completed Missed primary
Phase 2 NCT00889486 Apr 2009 → Apr 2010 diabetes mellitus, gastroparesis Tranzyme, Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as TZP-102 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00889486 ↗
2

NCT01664637 ↗

NCT01452815 ↗

Action Activate “TZP-102, a potent, oral, ghrelin receptor agonist” PMID 23848826 ↗ Jul 2013
1

“Ghrelin receptor agonist” CHEMBL4594424 ↗

Modality Protein / enzyme biologic — CHEMBL4594424 ↗
Route Oral “taken orally once per day” NCT00889486 ↗
Target GHSR “Ghrelin receptor agonist” CHEMBL4594424 ↗