Drugs / NUVISERTIB
last change Mar 2026 re-read 9 days ago

NUVISERTIB

also known as TP-3654 · SGI-9481

Small molecule

Developed for
cancer
Investigated by
Sumitomo Pharma America, Inc.

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07492355 Mar → May 2024 myelofibrosis Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT06389955 May → Aug 2023 — Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1 NCT03715504 Apr 2019 → Mar 2021 cancer Sumitomo Pharma America, Inc. Completed No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2026-03-18 Jazz Pharmaceuticals Results Jazz Pharmaceuticals to Present Compelling Clinical and Pre-Clinical Data Advancing Oncology Research at AACR 2026 jazzpharma.com ↗
Nuvisertib (TP-3654) and Dordaviprone (ONC201) synergize to reduce renal cell carcinoma cell viability

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as NUVISERTIB ChEMBL registry synonym — accepted as the source's own label CHEMBL3975308 ↗
Known as SGI-9481 ChEMBL registry synonym — accepted as the source's own label CHEMBL3975308 ↗
Known as TP-3654 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03715504 ↗
2

NCT07492355 ↗

NCT06389955 ↗

Action Inhibit “oral PIM inhibitor” NCT03715504 ↗
Modality Small molecule — CHEMBL3975308 ↗
Route Oral “TP-3654 by oral administration” NCT03715504 ↗