Drugs / SB773812
last change Oct 2007 re-read 2 minutes ago

SB773812

also known as GW773812

Small molecule targets DRD2, HTR2A via inhibition

Developed for
schizophrenia
Investigated by
GlaxoSmithKline

Trials 5 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT00500201 May → Jul 2007 schizophrenia GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00411866 Oct 2006 → Oct 2007 schizophrenia GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00269035 Jun 2005 → May 2007 schizophrenia GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00197093 Sep 2004 → ? schizophrenia GlaxoSmithKline Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00259870 Sep 2005 → Aug 2007 schizophrenia GlaxoSmithKline Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as SB773812 “A Placebo Controlled, Double-Blind, Randomised Study Investigating the Safety, Tolerability and Pharmacokinetics of Ascending Multiple Oral Doses of SB-773812 in Male and...” NCT00197093
7

“A Healthy Volunteer Study to Assess the Relative Bioavailability of 2 Forms of SB773812 Tablets.” NCT00500201

“single oral dose of SB-773812 20 milligrams (mg)” NCT00411866

NCT00259870

NCT00411866

NCT00197093

NCT00500201

NCT00269035

Known as GW773812 ChEMBL registry synonym — accepted as the source's own label CHEMBL5314394
Action Inhibit “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL5314394
1

“Dopamine D2 receptor antagonist” CHEMBL5314394

Modality Small molecule CHEMBL5314394
Route Oral “Ascending Multiple Oral Doses” NCT00197093
Target DRD2 “Dopamine D2 receptor antagonist” CHEMBL5314394
Target HTR2A “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL5314394