Drugs / PD-1 knockout TILs
last change Dec 2025 re-read 3 minutes ago

PD-1 knockout TILs

Cell therapy

Developed for
colorectal cancer
Investigated by
Ruijin Hospital

Trials 1

20252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07035002 Dec 2024 → Dec 2025 overdue colorectal cancer Ruijin Hospital Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as PD-1 knockout TILs ClinicalTrials.gov intervention name — accepted as the source's own label NCT07035002 ↗
Action Inhibit “gene editing technology to knockout PD-1” NCT07035002 ↗
Modality Cell therapy “TIL from tumor tissue of advanced colorectal cancer patients were cultured, modified and expanded in vitro, and then transfused back to the patients after quality control.” NCT07035002 ↗
Route Other “transfusing them back to the patient” NCT07035002 ↗