Drugs / PF-04531083
last change May 2012 re-read 2 minutes ago

PF-04531083

also known as PF-4531083

Small molecule targets SCN10A via inhibition

Investigated by
Pfizer

Trials 4 · a red edge is where a trial was stopped

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT01127906 Jun → Sep 2010 Pfizer Completed No outcome recorded
Phase 1 NCT01103739 Mar → May 2010 chronic pain syndrome Pfizer Completed No outcome recorded
Phase 1 NCT01012310 Nov 2009 → Feb 2010 Pfizer Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01512160 Oct 2011 → Mar 2012 Pfizer Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01119235 Comparator May → Jul 2010 chronic pain syndrome Pfizer Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as PF-04531083 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01103739
4

NCT01127906

NCT01012310

NCT01119235

NCT01512160

Known as PF-4531083 ChEMBL registry synonym — accepted as the source's own label CHEMBL3589904
Action Inhibit “Sodium channel protein type X alpha subunit blocker” CHEMBL3589904
Modality Small molecule CHEMBL3589904
Route Oral “multiple oral doses” NCT01012310
Target SCN10A “Sodium channel protein type X alpha subunit blocker” CHEMBL3589904