Drugs / METELIMUMAB
last change Sep 2003 re-read 3 minutes ago

METELIMUMAB

also known as CAT-192

Monoclonal antibody targets TGFB1 via inhibition

Developed for
systemic sclerosis
Investigated by
Cambridge Antibody Technology · Genzyme, a Sanofi Company

Trials 1

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT00043706 ? → Sep 2003 systemic sclerosis Genzyme, a Sanofi Company Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as METELIMUMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL2108431 ↗
Known as CAT-192 “Genzyme Corporation is currently investigating a human monoclonal antibody (CAT-192) that neutralizes active TGF-beta1.” NCT00043706 ↗
Action Inhibit “Transforming growth factor beta-1 inhibitor” CHEMBL2108431 ↗
1

“neutralizes active TGF-beta1” NCT00043706 ↗

Modality Monoclonal antibody “a human monoclonal antibody (CAT-192)” NCT00043706 ↗
Target TGFB1 “Transforming growth factor beta-1 inhibitor” CHEMBL2108431 ↗