Drugs / AS01B
AS01B
Trials 2 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT04026009 | Aug 2019 → May 2022 | Clostridium infectious disease | GlaxoSmithKline | Completed | No outcome recorded |
| Phase 1 | NCT00358332 | Nov 2006 → Dec 2007 | Plasmodium falciparum malaria | U.S. Army Medical Research and Development Command | Completed | No outcome recorded |
Also used as a comparator or background therapy in 4 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT03547245 Comparator | Jun 2018 → Jan 2020 | HIV infectious disease | International AIDS Vaccine Initiative | Completed | No outcome recorded |
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT03707808 Background | Jan 2018 → Dec 2025 overdue | malignant soft tissue neoplasm | University Hospital Brussels | Recruiting | No outcome recorded |
| Phase 1/2 | NCT02044198 Comparator | Mar → Dec 2014 | Plasmodium falciparum malaria | University of Oxford | Completed | No outcome recorded |
| Phase 1/2 | NCT01157897 Background | Jul 2010 → Jan 2012 | Plasmodium vivax malaria | U.S. Army Medical Research and Development Command | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | AS01B | “Plasmodium vivax malaria protein 001 (VMP001) with GSK Biologicals' Adjuvant System AS01B” NCT01157897 ↗ |
| Known as | FMP2.1 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02044198 ↗ |
| Known as | FMP2.1/AS02(A) | “The malaria vaccine FMP2.1/AS02(A) is a recombinant protein (FMP2.1) based on apical membrane antigen 1 (AMA1) from the 3D7 clone of P. falciparum, formulated in the Adjuvant...” PMID 20140214 ↗ Feb 2010 |
| Modality | Protein / enzyme biologic | “The malaria vaccine FMP2.1/AS02(A) is a recombinant protein (FMP2.1) based on apical membrane antigen 1 (AMA1) from the 3D7 clone of P. falciparum, formulated in the Adjuvant...” PMID 20140214 ↗ Feb 2010 |
| Route | Intramuscular | “administered by intramuscular injection” NCT00358332 ↗ |