Drugs / setrobuvir
last change Nov 2014 re-read 2 minutes ago

setrobuvir

also known as ANA598 · RO5466731 · STV

Small molecule

Developed for
chronic hepatitis C virus infection · hepatitis C virus infection
Investigated by
Hoffmann-La Roche

Trials 5 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT01714154 Nov 2012 → May 2013 Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT01612143 Jun → Sep 2012 Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT00782353 Oct 2008 → Mar 2009 chronic hepatitis C virus infection Hoffmann-La Roche Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01903954 Jan 2011 → May 2013 chronic hepatitis C virus infection Hoffmann-La Roche Completed No outcome recorded
Phase 2 NCT00978497 Sep 2009 → Apr 2010 hepatitis C virus infection Hoffmann-La Roche Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01628094 Background Jun 2012 → Nov 2013 chronic hepatitis C virus infection Hoffmann-La Roche Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as setrobuvir ClinicalTrials.gov intervention name — accepted as the source's own label NCT01714154
2

NCT01903954

NCT01612143

Known as ANA598 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00978497
1

NCT00782353

Known as RO5466731 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01628094
Known as STV “A Randomized, Open-label, Single Dose, Cross-over Study to Investigate the Relative Bioavailability of Setrobuvir (STV) Tablet Formulation Versus the Reference Setrobuvir...” NCT01612143
Action Inhibit “setrobuvir (a non-nucleoside HCV polymerase inhibitor)” PMID 25456558 Nov 2014
Modality Small molecule “setrobuvir (a non-nucleoside HCV polymerase inhibitor)” PMID 25456558 Nov 2014
1

CHEMBL1076263

Route Oral “ANA598, administered orally twice daily for 3 days” NCT00782353