Drugs / GPC-100
last change Oct 2025 re-read 2 minutes ago

GPC-100

also known as Burixafor

Small molecule targets CXCR4 via inhibition

Developed for
plasma cell myeloma
Investigated by
GPCR Therapeutics, Inc.

Trials 1 · a red edge is where a trial was stopped

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT05561751 Feb 2023 → Sep 2025 plasma cell myeloma GPCR Therapeutics, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as GPC-100 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05561751
Known as Burixafor “All patients will receive via IV 3.14 mg/kg GPC-100 (Burixafor) at least 2 hours prior to leukapheresis sessions” NCT05561751
Action Inhibit “GPC-100, a small molecule antagonist of CXCR4” PMID 37878624 Oct 2023
Modality Small molecule “GPC-100, a small molecule antagonist of CXCR4” PMID 37878624 Oct 2023
Route Intravenous “via IV infusion” NCT05561751
Target CXCR4 “GPC-100, a small molecule antagonist of CXCR4PMID 37878624 Oct 2023