Drugs / Oxypurinol
last change Apr 2011 re-read 2 minutes ago

Oxypurinol

also known as NSC-76239 · Oxipurinol

Small molecule targets XDH via inhibition

Developed for
congestive heart failure
Investigated by
Advanz Pharma · National Heart, Lung, and Blood Institute (NHLBI) · National Institutes of Health Clinical Center (CC)

Trials 3 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00102271 Jan 2005 → Apr 2011 National Heart, Lung, and Blood Institute (NHLBI) Completed No outcome recorded
Phase 1 NCT00072826 Nov 2003 → Aug 2007 sickle cell disease National Institutes of Health Clinical Center (CC) Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT00063687 Mar 2003 → Jun 2005 congestive heart failure Advanz Pharma Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Oxypurinol ClinicalTrials.gov intervention name — accepted as the source's own label NCT00072826
2

NCT00063687

NCT00102271

Known as NSC-76239 ChEMBL registry synonym — accepted as the source's own label CHEMBL859
Known as Oxipurinol ChEMBL registry synonym — accepted as the source's own label CHEMBL859
Action Inhibit “a xanthine oxidase (XO) inhibitor, oxypurinol” PMID 18549913 Jun 2008
1

“Xanthine dehydrogenase inhibitor” CHEMBL859

Modality Small molecule CHEMBL859
Route Oral oral oxypurinol” NCT00063687
Target XDH “Xanthine dehydrogenase inhibitor” CHEMBL859