Drugs / ER-100
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ER-100

Gene therapy (AAV / viral vector)

Developed for
non-arteritic anterior ischemic optic neuropathy · open-angle glaucoma
Investigated by
Life Biosciences Inc.

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07290244 Mar 2026 → May 2027 expected non-arteritic anterior ischemic optic neuropathy, open-angle glaucoma Life Biosciences Inc. Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2026-01-28 Life Biosciences Inc. Regulatory Life Biosciences Announces FDA Clearance of IND Application for ER-100 in Optic Neuropathies lifebiosciences.com ↗
2025-08-26 Life Biosciences Inc. Results Life Biosciences Presents New Data at ARDD 2025 on the Company’s Partial Epigenetic Reprogramming Platform in Liver and Ocular Diseases lifebiosciences.com ↗
2024-10-21 Life Biosciences Inc. Results Life Biosciences Presents at AAO Highlighting Progress of Nonhuman Primate Studies Evaluating Partial Epigenetic Reprogramming to Restore Visual Function lifebiosciences.com ↗
Furthermore, ER-100 significantly reduced deficits in pattern electroretinogram and axon density measures when administered in both prevention and rescue paradigms.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as ER-100 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07290244 ↗
Modality Gene therapy (AAV / viral vector) “modified adeno-associated virus (AAV) vector” NCT07290244 ↗
Route Intravitreal “administered via intravitreal injection” NCT07290244 ↗