Drugs / GB2064
last change Jun 2026 re-read 3 minutes ago

GB2064

also known as PAT-1251

Small molecule targets LOXL2 via inhibition

Developed for
myelofibrosis
Investigated by
Galecto Biotech AB · OPIS s.r.l

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04679870 Jun 2021 → Dec 2023 overdue myelofibrosis Galecto Biotech AB Active not recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as GB2064 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04679870 ↗
Known as PAT-1251 “GB2064 (formerly PAT-1251) is a high-affinity, selective, mechanism-based, small molecule inhibitor of LOXL2, administered twice a day” NCT04679870 ↗
Action Inhibit “inhibitor of LOXL2” NCT04679870 ↗
Modality Small molecule “small molecule inhibitor” NCT04679870 ↗
Route Oral “administered orally” NCT04679870 ↗
Target LOXL2 “inhibitor of LOXL2” NCT04679870 ↗