Drugs / FDL169
last change Feb 2020 re-read 3 minutes ago

FDL169

also known as Cftr corrector 2

Small molecule targets CFTR via restoration

Developed for
cystic fibrosis
Investigated by
Flatley Discovery Lab LLC

Trials 8

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT03527095 Apr → Jun 2018 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded
Phase 1 NCT03516331 Mar → Aug 2018 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded
Phase 1 NCT03424252 Dec 2017 → Jan 2018 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded
Phase 1 NCT03093714 Aug 2017 → Apr 2018 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded
Phase 1 NCT02680418 Dec 2015 → Feb 2016 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded
Phase 1 NCT02359357 Jan 2015 → Mar 2016 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT03756922 Nov 2018 → Feb 2020 cystic fibrosis Flatley Discovery Lab LLC Suspended No outcome recorded Stop: Business
Phase 1/2 NCT02767297 Apr → Oct 2016 cystic fibrosis Flatley Discovery Lab LLC Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as FDL169 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03093714 ↗
7

NCT02680418 ↗

NCT03527095 ↗

NCT03424252 ↗

NCT03516331 ↗

NCT02767297 ↗

NCT03756922 ↗

NCT02359357 ↗

Known as Cftr corrector 2 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095180 ↗
Action Restore “CFTR corrector” NCT03756922 ↗
Modality Small molecule — CHEMBL5095180 ↗
Route Oral “single oral administrations of FDL169” NCT02359357 ↗
Target CFTR “Cystic Fibrosis Transmembrane Regulator (CFTR) corrector” NCT03424252 ↗