Drugs / CCX354
last change Jul 2011 re-read 3 minutes ago

CCX354

also known as CCX354-C · GSK-2941266

Small molecule targets CCR1 via inhibition

Developed for
rheumatoid arthritis
Investigated by
Amgen

Trials 2

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT01027728 Dec 2009 → Jul 2010 rheumatoid arthritis Amgen Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01242917 Sep 2010 → Jul 2011 rheumatoid arthritis Amgen Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as CCX354 ChEMBL registry synonym — accepted as the source's own label CHEMBL4444976 ↗
Known as CCX354-C “The purpose of this study is to evaluate the safety and tolerability of multiple oral doses of CCX354-C at a number of dose levels in subjects with stable rheumatoid arthritis (RA).” NCT01027728 ↗
2

NCT01027728 ↗

NCT01242917 ↗

Known as GSK-2941266 ChEMBL registry synonym — accepted as the source's own label CHEMBL4444976 ↗
Action Inhibit “C-C chemokine receptor type 1 antagonist” CHEMBL4444976 ↗
Modality Small molecule — CHEMBL4444976 ↗
Route Oral “multiple oral doses” NCT01027728 ↗
Target CCR1 “C-C chemokine receptor type 1 antagonist” CHEMBL4444976 ↗