Drugs / Lamivudine/Zidovudine
last change Oct 2007 re-read 9 days ago

Lamivudine/Zidovudine

also known as Combivir
Developed for
HIV infectious disease
Investigated by
Glaxo Wellcome

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
— NCT00002217 — HIV infectious disease Glaxo Wellcome Completed No outcome recorded

News releases announcing trial results or a regulatory action · 5

DateIssuerRelease
2007-10-29 Gilead Sciences Results Gilead Announces 48-Week Data Evaluating Switching from Combivir(R) To Truvada(R) Among Virologically-Suppressed HIV Patients gilead.com ↗
In the SWEET (Simplification With Easier Emtricitabine and Tenofovir) study, patients who switched from Combivir to Truvada, both in combination with once-daily Sustiva(R) (efavirenz), experienced improvements in a number of treatment-related side effects.
2007-07-23 Gilead Sciences Results 144-Week Data from Gilead's Study 934 Comparing Truvada(R) to Combivir(R) Both in Combination with Sustiva(R) Presented At International AIDS Society Meeting in Sydney gilead.com ↗
Gilead Sciences, Inc. (Nasdaq:GILD) today announced the presentation of 144-week data from an ongoing clinical trial, Study 934, comparing a once-daily regimen of Truvada(R) (emtricitabine and tenofovir disoproxil fumarate) and Sustiva(R) (efavirenz) to a twice-daily regimen of Combivir(R) (lamivudine/zidovudine) with Sustiva once daily in treatment-naive adults with HIV.
2006-12-15 Gilead Sciences Results 96-Week Data From Gilead's Study 934 Comparing Viread(R) and Emtriva(R) to Combivir(R) Both in Combination With Sustiva(R) Published in Journal of Acquired Immune Deficiency Syndrome gilead.com ↗
Gilead Sciences, Inc. (Nasdaq:GILD) today announced the publication of 96-week data from an ongoing clinical trial, Study 934, in the Journal of Acquired Immune Deficiency Syndrome (JAIDS).
2006-08-14 Gilead Sciences Results 96-Week Data from Gilead's Study 934 Comparing Viread(R) and Emtriva(R) to Combivir(R) Both in Combination with Sustiva(R) Presented at XVI International AIDS Conference gilead.com ↗
Ninety-six week data are being presented by Joel Gallant, MD, Johns Hopkins University School of Medicine, Baltimore, at the XVI International AIDS Conference taking place August 13-18 in Toronto (Poster # TUPE0064).
2006-01-18 Gilead Sciences Results Data Comparing Viread(R) and Emtriva(R) to Combivir(R) as Part of Combination HIV Therapy Published in New England Journal of Medicine gilead.com ↗
Publication Describes Superior Viral Suppression with Fewer Adverse Events Leading to Discontinuation for Patients Taking Viread and Emtriva at 48 Weeks

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Lamivudine/Zidovudine ClinicalTrials.gov intervention name — accepted as the source's own label NCT00002217 ↗
Known as Combivir “In this open-label study antiretroviral-experienced patients receive Combivir (3TC/AZT tablet) plus 1592U89 (abacavir) and 141W94 twice daily for 48 weeks.” NCT00002217 ↗