Drugs / Englumafusp alfa
last change Nov 2024 re-read 9 days ago

Englumafusp alfa

also known as Ensomafusp alfa · RG-6076 · RO-7227166

Protein / enzyme biologic targets CD19

Developed for
non-Hodgkin lymphoma
Investigated by
Hoffmann-La Roche

Trials 1

20202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04077723 Aug 2019 → Mar 2027 expected non-Hodgkin lymphoma Hoffmann-La Roche Active not recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2024-11-05 Hoffmann-La Roche Results Roche to present new and encouraging long-term follow-up data across broad haematology portfolio at ASH 2024 roche.com ↗
Englumafusp alfa (CD19-4-1BBL) combined with glofitamab is safe and efficacious in patients with r/r B-NHL: extended follow up analysis of the dose-escalation part of Phase 1 trial BP41072

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Englumafusp alfa ClinicalTrials.gov intervention name — accepted as the source's own label NCT04077723 ↗
Known as Ensomafusp alfa ChEMBL registry synonym — accepted as the source's own label CHEMBL5095378 ↗
Known as RG-6076 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095378 ↗
Known as RO-7227166 ChEMBL registry synonym — accepted as the source's own label CHEMBL5095378 ↗
Modality Protein / enzyme biologic — CHEMBL5095378 ↗
Target CD19 “A CD19 Targeted 4-1BB Ligand” NCT04077723 ↗