oxazepam
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | SERAX | — | 1965-06-04 | fda.gov ↗ |
Trials 7
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 13 trials | ||||||
| Phase 1 | NCT03404817 | Mar → Jun 2018 | substance-related disorder | Embera NeuroTherapeutics, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT02856854 | Jul 2016 → Feb 2017 | substance-related disorder | Embera NeuroTherapeutics, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT00000661 | — | HIV infectious disease | National Institute of Allergy and Infectious Diseases (NIAID) | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT04933916 | Jun 2021 → Apr 2023 | nicotine dependence | Embera NeuroTherapeutics, Inc. | Terminated | No outcome recorded Stop: Business |
| Phase 21 trial | ||||||
| Phase 2 | NCT04501874 | Jul 2020 → Jul 2022 | substance-related disorder | Embera NeuroTherapeutics, Inc. | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT04868253 | May → Dec 2021 | nicotine dependence | Rose Research Center, LLC | Unknown | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT02374567 | Jan 2015 → Jun 2017 | anxiety disorder, dementia, depressive disorder, schizophrenia +1 | Hannover Medical School | Terminated | No outcome recorded |
| Comparator or background therapy4 trials | ||||||
| Phase 1 | NCT02406066 Comparator | Mar → Dec 2015 | substance-related disorder | Embera NeuroTherapeutics, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT02273453 Comparator | Feb → Jun 2003 | — | Boehringer Ingelheim | Completed | No outcome recorded |
| Phase 4 | NCT02090504 Comparator | Feb 2002 → Apr 2009 | alcohol dependence, alcohol withdrawal | Catholic University of the Sacred Heart | Completed | No outcome recorded |
| — | NCT00567814 Comparator | Dec 2007 → Nov 2008 | cocaine dependence | Embera NeuroTherapeutics, Inc. | Completed | No outcome recorded |
Evidence & citations 14 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | oxazepam | “EMB-001 is a combination of 2 drugs: the cortisol synthesis inhibitor, metyrapone (Metopirone®), and the benzodiazepine receptor agonist, oxazepam (original trade name Serax®;...” NCT04501874 ↗10“EMB-001 is a combination of 2 drugs: the cortisol synthesis inhibitor, metyrapone (Metopirone®), and the benzodiazepine receptor agonist, oxazepam (original trade name Serax®;...” NCT04933916 ↗ “EMB-001 is a proprietary combination of metyrapone (a cortisol synthesis inhibitor) and oxazepam (a short to medium acting benzodiazepine).” NCT04868253 ↗ “This is a study of EMB-001 (a combination of two FDA-approved drugs, metyrapone and oxazepam) in healthy adults.” NCT03404817 ↗ “EMB-001 is a combination of metyrapone (720mg per dose in this study) and oxazepam (24mg per dose in this study)” NCT02856854 ↗ |
| Known as | J3.308A | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Known as | Lederpam | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Known as | NSC-169448 | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Known as | Oxazepam civ | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Known as | Oxozepam | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Known as | Serax | “EMB-001 is a combination of 2 drugs: the cortisol synthesis inhibitor, metyrapone (Metopirone®), and the benzodiazepine receptor agonist, oxazepam (original trade name Serax®;...” NCT04933916 ↗1“EMB-001 is a combination of 2 drugs: the cortisol synthesis inhibitor, metyrapone (Metopirone®), and the benzodiazepine receptor agonist, oxazepam (original trade name Serax®;...” NCT04501874 ↗ |
| Known as | Serenid fte | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Known as | Temazepam impurity, oxazepam- | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Known as | WY-3498 | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Known as | Zaxopam | ChEMBL registry synonym — accepted as the source's own label CHEMBL568 ↗ |
| Action | Activate | “the benzodiazepine receptor agonist, oxazepam” NCT02856854 ↗ |
| Modality | Small molecule | “Benzodiazepines (such as oxazepam)” NCT00000661 ↗ |
| Route | Oral | “single oral dose oxazepam” NCT00000661 ↗ |