Drugs / MAb425
last change Jan 2014 re-read 3 minutes ago

MAb425

also known as Anti-EGFr-425

Monoclonal antibody targets EGFR

Developed for
anaplastic astrocytoma · glioblastoma · malignant glioma
Investigated by
Drexel University · Drexel University College of Medicine

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial · 1 met primary
Phase 2 NCT00589706 Jan 1985 → Dec 2012 malignant glioma Drexel University College of Medicine Completed Met primary
Phase not applicable1 trial
— NCT01317888 Jan 2010 → Jan 2014 anaplastic astrocytoma, glioblastoma Drexel University Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as mAb 425 “MAb425 anti-epidermal growth receptor) and Iodine-125 will be given as an injection for a total of three treatments each separated by one week.” NCT01317888 ↗
4

“anti-epidermal growth factor receptor 425 murine monoclonal antibody ((125)I-mAb 425)” PMID 20345222 ↗ Aug 2010

“MAb425 anti-epidermal growth receptor) and Iodine-125 will be given as an injection” NCT00589706 ↗

NCT00589706 ↗

NCT01317888 ↗

Known as Anti-EGFr-425 “Anti-Epidermal Growth Factor Receptor-425 (Anti-EGFr-425) Monoclonal Antibody Radiolabeled With 1-125” NCT01317888 ↗
Modality Monoclonal antibody “Anti-Epidermal Growth Factor Receptor-425 (Anti-EGFr-425) Monoclonal Antibody” NCT01317888 ↗
Route Intravenous “3 weekly intravenous injections” PMID 20345222 ↗ Aug 2010
Target EGFR “anti-epidermal growth factor receptor 425” NCT00589706 ↗