Drugs / RO6870810
RO6870810
also known as
(S)-JQ35 · Bet inhibitor ro6870810 · BET INHIBITOR TEN-010 · Jq-35, (s)- · Rg 6146 · TEN-010
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT03292172 | Nov 2017 → Feb 2019 | ovarian cancer, triple-negative breast carcinoma | Hoffmann-La Roche | Terminated | No outcome recorded Stop: Business |
| Phase 1 | NCT03255096 | Aug 2017 → Jul 2019 | high grade B-cell lymphoma | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 1 | NCT03068351 | Jun 2017 → Aug 2019 | plasma cell myeloma | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 1 | NCT02308761 | Nov 2014 → Aug 2017 | acute myeloid leukemia, myelodysplastic syndrome | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 1 | NCT01987362 | Oct 2013 → Oct 2017 | — | Hoffmann-La Roche | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | RO6870810 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03292172 ↗ |
| Known as | (S)-JQ35 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297423 ↗ |
| Known as | Bet inhibitor ro6870810 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297423 ↗ |
| Known as | BET INHIBITOR TEN-010 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297423 ↗ |
| Known as | Jq-35, (s)- | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297423 ↗ |
| Known as | Rg 6146 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297423 ↗ |
| Known as | TEN-010 | “RO6870810 (formerly TEN-010) is a small molecule, bromodomain and extra-terminal (BET) bromodomain inhibitor.” NCT02308761 ↗ |
| Action | Inhibit | “RO6870810 is a novel, small-molecule BET inhibitor.” PMID 33311588 ↗ Dec 2020 |
| Modality | Small molecule | “RO6870810 is a novel, small-molecule BET inhibitor.” PMID 33311588 ↗ Dec 2020 |
| Route | Subcutaneous | “RO6870810 will be administered by subcutaneous (SC) injection” NCT01987362 ↗ |