Drugs / ChiLob7/4
last change Jan 2015 re-read 3 minutes ago

ChiLob7/4

targets CD40 via activation

Developed for
B-cell neoplasm · cancer · non-Hodgkin lymphoma
Investigated by
Cancer Research UK

Trials 1

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01561911 Jul 2007 → Oct 2014 B-cell neoplasm, cancer, non-Hodgkin lymphoma Cancer Research UK Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ChiLob7/4 “This phase I study aimed to establish the biologic effects and MTD of the agonistic IgG1 chimeric anti-CD40 antibody ChiLob7/4 in patients (pts) with a range of CD40-expressing...” PMID 25589626 ↗ Jan 2015
1

NCT01561911 ↗

Action Activate “the agonistic IgG1 chimeric anti-CD40 antibody ChiLob7/4” PMID 25589626 ↗ Jan 2015
Route Intravenous “Chi Lob 7/4, given intravenously, weekly for 4 weeks” NCT01561911 ↗
Target CD40 “the agonistic IgG1 chimeric anti-CD40 antibody ChiLob7/4” PMID 25589626 ↗ Jan 2015