Drugs / AFACIFENACIN
last change Mar 2013 re-read 3 minutes ago

AFACIFENACIN

also known as Afacifenacina · Afacifenacine · NS-986 · SMP-986

Small molecule targets SCN10A, SCN11A via inhibition

Developed for
overactive bladder
Investigated by
ClinPhone, Inc. · Covance · Dainippon Sumitomo Pharma America · ICON Clinical Research · PPD Development, LP · Sumitomo Pharma America, Inc.

Trials 1

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00409539 Dec 2006 → Jun 2008 overactive bladder Sumitomo Pharma America, Inc. Completed No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2013-03-07 Sumitomo Pharma America, Inc. Dainippon Sumitomo Pharma and Nippon Shinyaku conclude a license agreement for SMP-986, a therapeutic agent for urology sumitomo-pharma.com ↗

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as AFACIFENACIN ChEMBL registry synonym — accepted as the source's own label CHEMBL3545165 ↗
Known as Afacifenacina ChEMBL registry synonym — accepted as the source's own label CHEMBL3545165 ↗
Known as Afacifenacine ChEMBL registry synonym — accepted as the source's own label CHEMBL3545165 ↗
Known as NS-986 ChEMBL registry synonym — accepted as the source's own label CHEMBL3545165 ↗
Known as SMP-986 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00409539 ↗
Action Inhibit “Sodium channel protein type XI alpha subunit blocker” CHEMBL3545165 ↗
1

“Sodium channel protein type X alpha subunit blocker” CHEMBL3545165 ↗

Modality Small molecule — CHEMBL3545165 ↗
Target SCN10A “Sodium channel protein type X alpha subunit blocker” CHEMBL3545165 ↗
Target SCN11A “Sodium channel protein type XI alpha subunit blocker” CHEMBL3545165 ↗