Every value below carries the sentence it was read from.
59 sources stand behind the page.
Field
Value
Cited text
Known as
bintrafusp alfa
“Bintrafusp alfa (M7824) is a novel first-in-class bifunctional fusion protein composed of a monoclonal antibody against PD-L1 fused to the extracellular domain of human...” NCT04235777 ↗33
“The purpose of the study is to evaluate the efficacy and safety of bintrafusp alfa (M7824) compared with pembrolizumab in participants with advanced NSCLC with high PD-L1-tumor...” NCT03631706 ↗
“Bintrafusp alfa (M7824) is a bifunctional fusion protein consisting of an anti-programmed death ligand 1 (PD-L1) antibody functioning as an immune checkpoint inhibitor and the...” NCT04327986 ↗
“Bintrafusp alfa (BA) is a bifunctional fusion protein composed of the extracellular domain of the transforming growth factor-β (TGF-β) receptor II fused to a human...” PMID 36066618 ↗Sep 2022
“An Open Label, Single-arm, Multi-center Phase 1b/2 Combination Study of M7824 (Bintrafusp Alfa) and Paclitaxel in Recurrent/Metastatic Gastric Cancer as a Second-line Treatment” NCT04835896 ↗
ChEMBL registry synonym — accepted as the source's own labelCHEMBL4298024 ↗
Known as
M7824
“In this study, the optimal dose of inhaled AZA will be established in patients with unresectable pulmonary metastases who are receiving the dual immune checkpoint...” NCT04648826 ↗27
“A Phase II Study of N-803 Alone or in Combination With BN-Brachyury Vaccine or Bintrafusp Alfa (M7824) for Participants With Castration Resistant Prostate Cancer” NCT05445882 ↗
“A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer” NCT04349280 ↗
“a bifunctional fusion protein targeting PD-L1 and TGF beta (M7824 (MSB0011359C)” NCT04491955 ↗
“Bintrafusp alfa (M7824 or MSB0011359C) is a bifunctional protein composed of the extracellular domain of the Transforming Growth Factor Beta Receptor 2 (TGF-BetaRII) receptor...” NCT04574583 ↗5
“1/ Arm 1-Gemcitabine + de-escalating dose of M7824 (MSB0011359C)” NCT03451773 ↗